Date Filer Title Filing Type Shares Traded Price Total Held
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 1,231 -- 8,585
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 101,918 -- 110,503
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 2,433 -- 112,936
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 254,275 -- --
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 52,720 -- --
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 4,362,062 -- --
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 104,167 -- --
Aug 23, 2018
Ten Percent Owner
Ten Percent Owner Form 4 Conversion of derivative security 591,184 -- 591,184
Aug 23, 2018
Ten Percent Owner
Ten Percent Owner Form 4 Conversion of derivative security 337,694 $4.59 929,878
Aug 23, 2018
Ten Percent Owner
Ten Percent Owner Form 4 Open market or private purchase of non-derivative or derivative security 15,000 $6.12 943,878

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.