Bionano Genomics Announces Publication of Study Using OGM for Detection of Balanced Chromosomal Rearrangements Found in Recurrent Pregnancy Loss
Researchers analyzed samples from 11 couples who dealt with RPL, had a history of an affected child or fetus with chromosome loss or gain, or had a history of infertility to determine OGM’s utility for detection of cryptic BCRs, which can significantly increase the risk of delivering abnormal offspring with congenital malformations or miscarriage for carrier couples. OGM showed 100% concordance with the results from fluorescence in situ hybridization (FISH) and sequencing analyses and revealed additional complex rearrangement events such as inverted aberrations, further refining potential genetic interpretation. The study authors highlighted challenges associated with using traditional methods and cited OGM’s rapid and robust detection of cryptic BCRs with a high resolution as evidence of its potential application as a first-line method in routine clinical genetic testing.
This publication can be found here: https://jmg.bmj.com/content/early/2022/06/15/jmedgenet-2022-108553
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This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “may,” “can,” “believe” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things, the ability and utility of OGM to detect cryptic BCRs. Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks and uncertainties associated with: the impact of the COVID-19 pandemic on our business and the global economy; general market conditions; changes in the competitive landscape and the introduction of competitive technologies or improvements to existing technologies; failure of future study results to support those demonstrated in the paper referenced in this press release; failure OGM to detect cryptic BCRs; changes in our strategic and commercial plans; our ability to obtain sufficient financing to fund our strategic plans and commercialization efforts; the ability of medical and research institutions to obtain funding to support adoption or continued use of our technologies; and the risks and uncertainties associated with our business and financial condition in general, including the risks and uncertainties described in our filings with the
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Source: Bionano Genomics