Bionano Genomics Announces Publication of the First Study to Combine OGM and NGS to Evaluate Myeloid Cancers
- Whole genome analysis by OGM together with analysis using a 523-gene NGS panel can perform better and cost less than analysis with karyotyping, FISH, and a 54-gene NGS panel
- First study to publish results using NxClinical software for simultaneous visualization and interpretation of sequence and copy number variants from NGS and OGM data
This study reported superior performance as compared to standard methods and
“This research demonstrated that the combination of OGM and a 523-gene NGS panel is superior to standard methods and cost effective for comprehensive genomic profiling of myeloid cancers. When compared to whole-genome sequencing approaches that others have suggested, I believe it has better detection performance at a lower cost,” commented Dr. Ravindra Kolhe, Associate Dean for Translational Research at Medical College of Georgia and Director of the Georgia Esoteric and Molecular Laboratory at Augusta University. “With new tools to simultaneously visualize sequence variants and structural variants, we are well-positioned to move this approach into routine use, which we expect will deepen our understanding of hematological malignancies.”
The research, led by Dr. Kolhe’s team at the
“We believe this publication demonstrates the advantages of performing OGM side-by-side with NGS, for a combined workflow that can provide a more comprehensive, accurate detection of genetic variants at a cost and complexity that is practical for laboratories,” commented Erik Holmlin, PhD, President and Chief Executive Officer of Bionano. “With NxClinical software that allows for combined visualization of sequence and structural variants, we believe we have provided a tool that can make a combined OGM and NGS approach simple, scalable and superior to traditional methods.”
The study is published online at medRxiv: https://www.medrxiv.org/content/10.1101/2022.01.15.22269355v1?ct=
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Forward-Looking Statements of
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “may,” “will,” “expect,” “plan,” “anticipate,” “estimate,” “intend” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things, the ability of combined OGM and NGS workflows to provide a comprehensive evaluation of myeloid cancers, the potential benefits of combining OGM and NGS, including superior performance and cost-effectiveness as compared to SOC methods, and the potential for a combination of OGM and NGS to become the standard of care. Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks and uncertainties associated with: the impact of the COVID-19 pandemic on our business and the global economy; general market conditions; changes in the competitive landscape, including the introduction of competitive technologies or improvements in existing technologies; failure of future study results to support those referenced in this press release; changes in our strategic and commercial plans; our ability to obtain sufficient financing to fund our strategic plans and commercialization efforts; the ability of medical and research institutions to obtain funding to support adoption or continued use of our technologies; and the risks and uncertainties associated with our business and financial condition in general, including the risks and uncertainties described in our filings with the
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Source: Bionano Genomics