Bionano Announces 9 Poster Presentations and Introduces New High Throughput Stratys™ System at the American Association for Cancer Research Annual Meeting
- Nine scientific posters will illustrate the application of optical genome mapping (OGM) in cancer research areas including hematological malignancies, solid tumors, and applications in cell and gene therapy, cell manufacturing and bioprocessing quality control
- Bionano is introducing its new Stratys™ system for high throughput OGM to the cancer research community
- Bionano will preview VIA™ 7.1 software, an upcoming advancement to the Company’s software for visualization, interpretation and reporting of OGM, next-generation sequencing (NGS) and microarray data. VIA 7.1 includes new and improved capabilities for cancer research including improved aneuploidy detection with variant allele fraction (VAF) as low as 5%, enhanced structural variant (SV) visualization with VIA Circos plots, quality scores for SV detection, and streamlined interpretation with automated classification
Bionano will introduce its new Stratys™ system, which offers higher throughput and improved sample flexibility, to the cancer research community at the conference. The Company will also preview VIA™ 7.1 software, an upcoming advancement to its software for visualization, interpretation and reporting of OGM, NGS, and microarray data. VIA 7.1 includes new and improved capabilities for cancer research, including automated detection and interpretation of aneuploidies at a 5% variant allele fraction, providing researchers with greater insights into tumor initiation, progression and treatment resistance. The software also features quality scores for SV detection, enhanced visualization for accurate interpretation of complex datasets with VIA Circos plots, and streamlined, customizable reporting options.
Nine scientific poster presentations will illustrate OGM’s utility for cancer research in areas including solid tumors, hematological malignancies, as well as applications in cell and gene therapy and cell manufacturing and bioprocessing quality control.
Poster presentations on OGM include:
Abstract/ Poster Number |
Title | Authors | Presented |
336/24 | Genome Integrity Assessment by Optical Genome Mapping for Cell Manufacturing/Bioprocessing Applications | Pang A. | Section 14 |
2271/12 | Conservation and Faithful Representation of Circular Extrachromosomal DNA in Orthotopic Patient-Derived Medulloblastoma Xenografts | Kenkre R. | Section 35 |
2337/15 | Accelerated Optical Genome Mapping Analysis with |
Section 37 |
|
2012/28 | Extrachromosomal DNA Promotes Drug Resistance in Pancreatic Ductal Adenocarcinoma Cells | Vorberg T. | Section 26 |
3492/14 | Comprehensive Analysis of Hematological Malignancies with Optical Genome Mapping and Bionano VIA™ Software | Wisotsky J. | Section 34 |
2860/16 | High-Resolution Mapping of Oncogenic Structural Changes in Osteosarcoma | Clugston A.S. | Section 11 |
3551/11 | Continued Analysis of Extensive Data Towards Genome in a Bottle Benchmarks for a New Tumor |
Wagner J. | Section 36 |
4895/20 | Optical Genome Mapping Analysis Across Multiple Solid Tumor Types in Bionano VIA™ Software | Al-Saffar S. | Section 35 |
6257/27 | Genome Wide, High-Throughput, High-Resolution Structural Variation Detection at Low Variant Allele Fraction for Oncology Samples | Hastie A. | Section 37 |
“We are excited to participate in AACR’s annual meeting, where data that will be shared will point to the continued expansion of OGM into clinical research applications for hematological malignancies and solid tumors and highlight progress toward our goal of making OGM an essential tool in the arsenal of cancer researchers. We believe cancer is a disease of structural variation and that OGM and VIA, our software solution which has added features for cancer research and analysis, have the potential to make an impact in the fight against cancer,” commented
More details on the conference can be found here.
About Bionano
Bionano is a provider of genome analysis solutions that can enable researchers and clinicians to reveal answers to challenging questions in biology and medicine. The Company’s mission is to transform the way the world sees the genome through OGM solutions, diagnostic services and software. The Company offers OGM solutions for applications across basic, translational and clinical research. Through its Lineagen, Inc. d/b/a Bionano Laboratories business, the Company also provides diagnostic testing for patients with clinical presentations consistent with autism spectrum disorder and other neurodevelopmental disabilities. The Company also offers an industry-leading, platform-agnostic software solution, which integrates next-generation sequencing and microarray data designed to provide analysis, visualization, interpretation and reporting of copy number variants, single-nucleotide variants and absence of heterozygosity across the genome in one consolidated view. The Company additionally offers nucleic acid extraction and purification solutions using proprietary isotachophoresis technology. For more information, visit www.bionano.com, www.bionanolaboratories.com or www.purigenbio.com.
Unless specifically noted otherwise, Bionano’s OGM products are for research use only and not for use in diagnostic procedures.
Forward-Looking Statements of Bionano
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “believe,” “potential,” “will,” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things, OGM’s utility for cancer research including hematological malignancies and solid tumors; OGM’s utility for applications in cell and gene therapy, cell manufacturing and bioprocessing quality control; the utility of OGM for research in the areas reported in the presentations given and the posters made available at AACR’s annual 2024 meeting; the growth and adoption of OGM for use in cancer research or applications in cell and gene therapy, cell manufacturing and bioprocessing quality control; the ability and utility of our Stratys system and VIA 7.1 software to drive market adoption of OGM and to be useful for the automated detection and interpretation of aneuploidies and drive greater insights into tumor initiation, progression and treatment resistance. Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks and uncertainties associated with: global and macroeconomic events, such as the impact of the global pandemics, bank failures, interest rate changes, supply disruptions, and the ongoing conflicts in the
CONTACTS
Company Contact:
+1 (858) 888-7610
eholmlin@bionano.com
Investor Relations:
+1 (858) 888-7625
IR@bionano.com
Source: Bionano Genomics