Publication Recommends OGM for Analysis of Hematological Neoplasms Due to Streamlined Structural Variant Detection and High Concordance with Traditional Cytogenetic Methods
Researchers analyzed samples from 69 individuals referred to a clinical lab for cytogenetic analysis to assess OGM as an approach to provide cytogenetic profiling in hematological neoplasms that included acute myeloid leukemia (AML), chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL). OGM’s technical performance resulted in a 100% first-pass rate, with concordance to traditional methods showing a sensitivity of 98.7%, a specificity of 100%, and an accuracy of 99.2%. OGM identified several additional structural variants (SVs) not detected by other methods, revealing the genomic architecture in these neoplasms that the study authors believe may provide an opportunity for better tumor classification, prognostication, risk-stratification, and therapy selection.
This publication can be found here: https://www.jmdjournal.org/article/S1525-1578(22)00290-2/fulltext
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This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “believe,” “potential,” “may,” “believe” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things, the utility of OGM to provide cytogenetic profiling in hematological neoplasms that included acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL). Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks and uncertainties associated with: the impact of the COVID-19 pandemic on our business and the global economy; general market conditions; changes in the competitive landscape and the introduction of competitive technologies or improvements to existing technologies; failure of OGM to be adopted as a tool for cytogenetic profiling in hematological neoplasms that included acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL); future study results contradicting the results reported in the publication referenced above; changes in our strategic and commercial plans; our ability to obtain sufficient financing to fund our strategic plans and commercialization efforts; the ability of medical and research institutions to obtain funding to support adoption or continued use of our technologies; and the risks and uncertainties associated with our business and financial condition in general, including the risks and uncertainties described in our filings with the
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Source: Bionano Genomics