Hamilton and Bionano Genomics Announce World’s First Ultra High Molecular Weight DNA Extraction Automation Solution for OGM
Extraction of UHMW DNA of high quality and quantity is an important prerequisite and first step in Bionano’s sample preparation workflow. UHMW DNA extraction is generally performed manually by highly trained and experienced laboratory personnel, limiting volume and application in routine sample preparation.
By combining Hamilton’s long-standing expertise in automating genomic workflows through precision engineering of automated liquid handling solutions and consumables, and Bionano’s knowledge in extraction, enzymatic treatment and analysis of UHMW DNA molecules, the companies have developed the world’s first walk-away automation solution for UHMW DNA extraction.
Hamilton’s Long String VANTAGE is the first Assay Ready Workstation solution in Hamilton’s Long String Genomics product program and supports extraction of UHMW DNA at increased scale. Running the Bionano Prep SP Blood and Cell Culture DNA Isolation Kit, customers can obtain up to 12 UHMW DNA samples in less than 4 hours with high consistency and reproducibility. This workflow has the potential to double manual output, with increased confidence in sample yields and DNA quality.
The companies plan to collaborate with select clinical research laboratories to test and further develop applications for the use of the Long String VANTAGE and the Bionano Prep SP kits and anticipate commercial release of some of these workflows by the end of 2022.
“Hamilton is highly committed to empowering genomic sciences and diagnostics with innovative products and applications by collaborating with leading kit and technology providers,” Dr.
“The outcomes of this partnership with
Bionano Genomics is a provider of genome analysis solutions that can enable researchers and clinicians to reveal answers to challenging questions in biology and medicine. The Company’s mission is to transform the way the world sees the genome through OGM solutions, diagnostic services and software. The Company offers OGM solutions for applications across basic, translational and clinical research. Through its Lineagen business, the Company also provides diagnostic testing for patients with clinical presentations consistent with autism spectrum disorder and other neurodevelopmental disabilities. Through its BioDiscovery business, the Company also offers an industry-leading, platform-agnostic software solution, which integrates next-generation sequencing and microarray data designed to provide analysis, visualization, interpretation and reporting of copy number variants, single-nucleotide variants and absence of heterozygosity across the genome in one consolidated view. For more information, visit www.bionanogenomics.com, www.lineagen.com or www.biodiscovery.com
Forward-Looking Statements of
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “can,” “potential,” “plan,” “expect,” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things, the anticipated benefits and improvements resulting from the use of Hamilton’s Long String VANTAGE, or the ability of that system to reliably and consistently isolate high quality and sufficient quantity of UHMW DNA for use with optical genome mapping. Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks and uncertainties associated with: the impact of the COVID-19 pandemic on our business and the global economy; general market conditions; changes in the competitive landscape and the introduction of competitive technologies or improvements in existing technologies; changes in our strategic and commercial plans; our ability to obtain sufficient financing to fund our strategic plans and commercialization efforts; the ability of medical and research institutions to obtain funding to support adoption or continued use of our technologies; and the risks and uncertainties associated with our business and financial condition in general, including the risks and uncertainties described in our filings with the
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Source: Bionano Genomics