Bionano Genomics Announces Major Updates to Its Solve™ and Access™ Data Solutions Adding Significant New Variant Detection, Analysis and Reporting Capabilities for Optical Genome Mapping on the Saphyr® System
New OGM capabilities include the means to detect more clinically-relevant variants such as absence of heterozygosity (AOH) and allelic imbalance, the first two classes of variations that are typically considered as sequence rather than structural variants. The updates will also enable users to visualize chromosomal AOH across the genome similarly to single nucleotide polymorphism (SNP) microarrays. In addition, OGM users will have the ability to detect uniparental isodisomy UPD, regions identical by decent (IBD), triploidy and improved characterization of mosaic SVs through variant allele fraction (VAF) plots.
Also as part of this release, the family of EnFocus™ targeted analysis panels now includes one for Fragile X, a repeast expansion disorder. EnFocus Fragile X is an analytical routine that automates the process of sizing the Fragile X repeat with high accuracy, precision and sensitivity, thereby reducing the time to results for researchers.
Bionano has streamlined the analytical workflow tied to OGM through this software release. The new workflow enables all SVs detected by Solve and analyzed with Access to be named and classified using standard terminology according to the 2020 International System for Human Cytogenomic Nomenclature (ISCN). This new classification is expected to simplify the reporting and interpretation of research findings, making it easier to compare information across other databases.
“These ongoing improvements in the performance of our software for detecting SVs, as well as the tools for interpreting and reporting calls, continue to impress me,” said
About
Bionano is a provider of genome analysis solutions that can enable researchers and clinicians to reveal answers to challenging questions in biology and medicine. The Company’s mission is to transform the way the world sees the genome through optical genome mapping (OGM) solutions, diagnostic services and software. The Company offers OGM solutions for applications across basic, translational and clinical research. Through its
Forward-Looking Statements of
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “may,” “will,” “expect,” “plan,” “anticipate,” “estimate,” “intend” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) convey uncertainty of future events or outcomes and are intended to identify these forward-looking statements. Forward-looking statements include statements regarding our intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things: the expected benefits and significance of the Solve and Access upgrades; and our work to integrate our variant detection technology with NxClinical’s visualization, interpretation and reporting capabilities, including the products developed through such integration. Each of these forward-looking statements involves risks and uncertainties. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include the risks and uncertainties associated with: our ability to integrate BioDiscovery’s capabilities with our technology; issues related to the release of new products; the impact of the COVID-19 pandemic on our business and the global economy; general market conditions; changes in the competitive landscape and the introduction of competitive products; our hiring efforts may not achieve the anticipated results; changes in our strategic and commercial plans; our ability to obtain sufficient financing to fund our strategic plans and commercialization efforts; the ability of medical and research institutions to obtain funding to support adoption or continued use of our technologies; the loss of key members of management and our commercial team; and the risks and uncertainties associated with our business and financial condition in general, including the risks and uncertainties described in our filings with the
CONTACTS
Company Contact:
+1 (858) 888-7610
eholmlin@bionanogenomics.com
Investor Relations:
+1 (858) 366-3243
amy@juniper-point.com
Media Relations:
Seismic
+1 (503) 799-7520
michael@teamseismic.com
Source: Bionano Genomics