Date Filer Title Filing Type Shares Traded Price Total Held
Aug 21, 2018
Director, Ten Percent Owner
Director, Ten Percent Owner Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
Aug 21, 2018
Director, Ten Percent Owner
Director, Ten Percent Owner Form 3 Initial Statement of Beneficial Ownership of Securities -- -- --
Aug 23, 2018
Chief Operating Officer
Chief Operating Officer Form 4 Open market or private purchase of non-derivative or derivative security 815 $6.12 815
Aug 23, 2018
Chief Operating Officer
Chief Operating Officer Form 4 Open market or private purchase of non-derivative or derivative security 815 -- 815
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 5,941 -- 7,354
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 1,231 -- 8,585
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 101,918 -- 110,503
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 2,433 -- 112,936
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 254,275 -- --
Aug 23, 2018
Chief Scientific Officer
Chief Scientific Officer Form 4 Conversion of derivative security 52,720 -- --

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.